Source : Webster's Revised Unabridged Dictionary (1913)

Endermic \En*der"mic\, a. [Gr. ? in + ? skin.] (Med.)
   Acting through the skin, or by direct application to the
   skin.

   {Endermic method}, that in which the medicine enters the
      system through the skin, being applied either to the sound
      skin, or to the surface denuded of the cuticle by a
      blister.