Source : Webster's Revised Unabridged Dictionary (1913)

Melpomene \Mel*pom"e*ne\, n. [L., fr. Gr. ?, lit., the
   songstress, fr. ?, ?, to sing.]
   1. (Class. Myth.) The Muse of tragedy.

   2. (Astron.) The eighteenth asteroid.

Source : WordNet®

Melpomene
     n : (Greek mythology) the Muse of tragedy