Pepperidge \Pep"per*idge\, n. [Cf. NL. berberis, E. barberry.] (Bot.) A North American tree ({Nyssa multiflora}) with very tough wood, handsome oval polished leaves, and very acid berries, -- the sour gum, or common tupelo. See {Tupelo}. [Written also {piperidge} and {pipperidge}.] {Pepperidge bush} (Bot.), the barberry.