Perspire \Per*spire"\, v. i. [imp. & p. p. {Perspired}; p. pr. & vb. n. {Perspiring}.] [L. perspirare to breathe through; per + spirare. See {Per-}, and {Spirit}.] 1. (Physiol.) To excrete matter through the skin; esp., to excrete fluids through the pores of the skin; to sweat. 2. To be evacuated or excreted, or to exude, through the pores of the skin; as, a fluid perspires.