Source : Webster's Revised Unabridged Dictionary (1913)

Estrange \Es*trange"\, v. t. [imp. & p. p. {Estranged}; p. pr. &
   vb. n. {Estranging}.] [OF. estrangier to remove, F.
   ['e]tranger, L. extraneare to treat as a stranger, from
   extraneus strange. See {Strange}.]
   1. To withdraw; to withhold; hence, reflexively, to keep at a
      distance; to cease to be familiar and friendly with.

            We must estrange our belief from everything which is
            not clearly and distinctly evidenced. --Glanvill.

            Had we . . . estranged ourselves from them in things
            indifferent.                          --Hooker.

   2. To divert from its original use or purpose, or from its
      former possessor; to alienate.

            They . . . have estranged this place, and have
            burned incense in it unto other gods. --Jer. xix. 4.

   3. To alienate the affections or confidence of; to turn from
      attachment to enmity or indifference.

            I do not know, to this hour, what it is that has
            estranged him from me.                --Pope.

            He . . . had pretended to be estranged from the
            Whigs, and had promised to act as a spy upon them.
                                                  --Macaulay.

Source : WordNet®

estranging
     adj : making one feel out of place or alienated; "the landscape
           was estranging"