Source : Webster's Revised Unabridged Dictionary (1913)

Loco disease \Loco disease\ (Veter.)
   A chronic nervous affection of cattle, horses, and sheep,
   caused by eating the loco weed and characterized by a slow,
   measured gait, high step, glassy eyes with defective vision,
   delirium, and gradual emaciation.

Source : WordNet®

loco disease
     n : a disease of livestock caused by locoweed poisoning;
         characterized by weakness and lack of coordination and
         trembling and partial paralysis [syn: {locoism}]