louse up v : make a mess of, destroy or ruin; "I botched the dinner and we had to eat out"; "the pianist screwed up the difficult passage in the second movement" [syn: {botch}, {bumble}, {fumble}, {botch up}, {muff}, {blow}, {flub}, {screw up}, {ball up}, {spoil}, {muck up}, {bungle}, {fluff}, {bollix}, {bollix up}, {bollocks}, {bollocks up}, {bobble}, {mishandle}, {foul up}, {mess up}, {fuck up}]