Source : Webster's Revised Unabridged Dictionary (1913)

Murrain \Mur"rain\, n. [OE. moreine, OF. morine, fr. OF. morir,
   murir, 8die, L. mori, moriri.] (Far.)
   An infectious and fatal disease among cattle. --Bacon.

   {A murrain on you}, may you be afflicted with a pestilent
      disease. --Shak.

Murrain \Mur"rain\, a.
   Having, or afflicted with, murrain.

Source : WordNet®

murrain
     n : any plaguelike disease of domestic animals