Source : Webster's Revised Unabridged Dictionary (1913)

Predisposition \Pre*dis`po*si"tion\, n.[Pref. pre- +
   disposition: cf. F. pr['e]disposition.]
   1. The act of predisposing, or the state of being
      predisposed; previous inclination, tendency, or
      propensity; predilection; -- applied to the mind; as, a
      predisposition to anger.

   2. Previous fitness or adaptation to any change, impression,
      or purpose; susceptibility; -- applied to material things;
      as, the predisposition of the body to disease.

Source : WordNet®

predisposition
     n 1: susceptibility to a pathogen [syn: {sensitivity}]
     2: an inclination beforehand to interpret statements in a
        particular way
     3: a disposition in advance to react in a particular way