Source : Webster's Revised Unabridged Dictionary (1913)

Scleroderma \Scler`o*der"ma\, n. [NL.] (Med.)
   A disease of adults, characterized by a diffuse rigidity and
   hardness of the skin.

Source : WordNet®

scleroderma
     n 1: an autoimmune disease that affects the blood vessels and
          connective tissue; fibrous connective tissue is
          deposited in the skin [syn: {dermatosclerosis}]
     2: genus of poisonous fungi having hard-skinned fruiting
        bodies: false truffles [syn: {genus Scleroderma}]