Sambo \Sam"bo\, n. [Sp. zambo, sambo.] A colloquial or humorous appellation for a negro; sometimes, the offspring of a black person and a mulatto; a zambo. Sambo \Sam"bo\, n. [Sp. zambo bandy-legged, the child of a negro and an Indian; prob. of African origin.] 1. A negro; sometimes, the offspring of a black person and a mulatto. [Colloq. or Humorous]