Source : Webster's Revised Unabridged Dictionary (1913)

Self-annihilation \Self`-an*ni`hi*la"tion\, n.
   Annihilation by one's own acts; annihilation of one's
   desires. --Addison.

Source : WordNet®

self-annihilation
     n : the act of killing yourself; "it is a crime to commit
         suicide" [syn: {suicide}, {self-destruction}]