Source : Webster's Revised Unabridged Dictionary (1913)

Splenetic \Splen"e*tic\, a. [L. spleneticus: cf. F.
   spl['e]n['e]tique. See {Spleen}.]
   Affected with spleen; malicious; spiteful; peevish; fretful.
   ``Splenetic guffaw.'' --G. Eliot.

         You humor me when I am sick; Why not when I am
         splenetic?                               --Pope.

   Syn: Morese; gloomy; sullen; peevish; fretful.

Splenetic \Splen"e*tic\, n.
   A person affected with spleen.

Source : WordNet®

splenetic
     adj 1: of or relating to the spleen [syn: {splenic}, {lienal}]
     2: very irritable; "bristly exchanges between the White House
        and the press"; "he became prickly and spiteful"; "witty
        and waspish about his colleagues" [syn: {bristly}, {prickly},
         {waspish}]