Source : Webster's Revised Unabridged Dictionary (1913)

Uptown \Up*town"\, adv.
   To or in the upper part of a town; as, to go uptown. [Colloq.
   U. S.]

Uptown \Up"town`\, a.
   Situated in, or belonging to, the upper part of a town or
   city; as, a uptown street, shop, etc.; uptown society.
   [Colloq. U. S.]

Source : WordNet®

uptown
     adj : of or located in the upper part of a town; "uptown
           residential areas" [ant: {downtown}]
     n : a residential part of town away from the central commercial
         district
     adv : toward or in the upper part of town [ant: {downtown}]